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Publications

Read on to find out more about our latest work

2022

SARS-CoV2 mRNA Vaccine-Specific B-, T- and Humoral Responses in Adolescents After Kidney Transplantation. Sattler A, Thumfart J, Tóth L, Schrezenmeier E, Proß V, Stahl C, Siegle J, He A, Thole LML, Ludwig C, Straub-Hohenbleicher H, Friedersdorff F, Jahrsdörfer B, Schrezenmeier H, Bufler P, Kotsch K. Transpl Int. 2022 Aug 4;35:10677.

 

Renal inflamm-aging provokes intra-graft inflammation following experimental kidney transplantation. He A, Sarwar A, Thole LML, Siegle J, Sattler A, Ashraf MI, Proß V, Stahl C, Dornieden T, Bergmann Y, Ritschl PV, Ebner S, Hublitz KW, Stamatiades EG, Bülow RD, Boor P, Kotsch K. Am J Transplant. 2022 Nov;22(11):2529-2547. 

 

Temporary antimetabolite treatment hold boosts SARS-CoV-2 vaccination-specific humoral and cellular immunity in kidney transplant recipients.

Schrezenmeier E, Rincon-Arevalo H, Jens A, Stefanski AL, Hammett C, Osmanodja B, Koch N, Zukunft B, Beck J, Oellerich M, Proß V, Stahl C, Choi M, Bachmann F, Liefeldt L, Glander P, Schütz E, Bornemann-Kolatzki K, López Del Moral C, Schrezenmeier H, Ludwig C, Jahrsdörfer B, Eckardt KU, Lachmann N, Kotsch K, Dörner T, Halleck F, Sattler A, Budde K.JCI Insight. 2022 May 9;7(9):e157836. doi: 10.1172/jci.insight.157836.

 

Kidney Perfusion in Contrast-Enhanced Ultrasound (CEUS) Correlates with Renal Function in Living Kidney Donors. El-Bandar N, Lerchbaumer MH, Peters R, Maxeiner A, Kotsch K, Sattler A, Miller K, Schlomm T, Hamm B, Budde K, Liefeldt L, Fischer T, Friedersdorff F.J Clin Med. 2022 Feb 1;11(3):791. doi: 10.3390/jcm11030791.

2021

B cell numbers predict humoral and cellular response upon SARS-CoV-2 vaccination among patients treated with rituximab. Stefanski AL, Rincon-Arevalo H, Schrezenmeier E, Karberg K, Szelinski F, Ritter J, Jahrsdörfer B, Schrezenmeier H, Ludwig C, Sattler AKotsch K, Chen Y, Claußnitzer A, Haibel H, Proft F, Guerra G, Durek P, Heinrich F, Ferreira-Gomes M, Burmester GR, Radbruch A, Mashreghi MF, Lino AC, Dörner T. Arthritis Rheumatol. 2022 Jun;74(6):934-947. doi: 10.1002/art.42060. Epub 2022 Apr 17.

 

Reduced mitochondrial respiration in T cells of patients with major depressive disorder.  Gamradt S, Hasselmann H, Taenzer A, Brasanac J, Stiglbauer V, Sattler A, Sajitz-Hermstein M, Kierszniowska S, Ramien C, Nowacki J, Mascarell-Maricic L, Wingenfeld K, Piber D, Ströhle A, Kotsch K, Paul F, Otte C, Gold SM.iScience. 2021 Oct 16;24(11):103312. doi: 10.1016/j.isci.2021.103312. eCollection 2021 Nov 19.

B and T Cell Responses after a Third Dose of SARS-CoV-2 Vaccine in Kidney Transplant Recipients. Schrezenmeier E, Rincon-Arevalo H, Stefanski AL, Potekhin A, Straub-Hohenbleicher H, Choi M, Bachmann F, Pross V, Hammett C, Schrezenmeier H, Ludwig C, Jahrsdörfer B, Lino A, Eckardt KU, Kotsch K, Döerner T, Budde K, Sattler A, Halleck F. J Am Soc Nephrol. 2021 Oct 19;32(12):3027-33. doi: 10.1681/ASN.2021070966. Online ahead of print.PMID: 34667083

T- and B-cell therapy in solid organ transplantation: current evidence and future expectations. 

Pilat N, Lefsihane K, Brouard S, Kotsch K, Falk C, Steiner R, Thaunat O, Fusil F, Montserrat N, Amarelli C, Casiraghi F. Transpl Int. 2021 Sep;34(9):1594-1606. doi: 10.1111/tri.13972.

Signatures and Specificity of Tissue-Resident Lymphocytes Identified in Human Renal Peritumor and Tumor Tissue. Dornieden T, Sattler A, Pascual-Reguant A, Ruhm AH, Thiel LG, Bergmann YS, Thole LML, Köhler R, Kühl AA, Hauser AE, Boral S, Friedersdorff F, Kotsch K.  J Am Soc Nephrol. 2021 Sep;32(9):2223-2241. doi: 10.1681/ASN.2020101528. Epub 2021 Jun 1.

Expression of MICA in Zero Hour Biopsies Predicts Graft Survival After Liver Transplantation. Resch T, Hackl H, Esser H, Günther J, Schwelberger H, Ritschl PV, Ebner S, Maglione M, Mellitzer V, Biebl M, Öllinger R, Zoller H, Schneeberger S, Kotsch K. Front. Immunol. 2021 Jul 20;12:606146. doi: 10.3389/fimmu.2021.606146. eCollection 2021.

Impaired Humoral and Cellular Immunity after SARS-CoV2 BNT162b2 (Tozinameran) Prime-Boost Vaccination in Kidney Transplant Recipients. Arne Sattler, Eva Schrezenmeier, Ulrike A Weber, Alexander Potekhin, Friederike Bachmann, Henriette Straub-Hohenbleicher, Klemens Budde, Elena Storz, Vanessa Proß, Yasmin Bergmann, Linda ML Thole, Caroline Tizian, Oliver Hölsken, Andreas Diefenbach, Hubert Schrezenmeier, Bernd Jahrsdörfer, Tomasz Zemojtel, Katharina Jechow, Christian Conrad, Sören Lukassen, Diana Stauch, Nils Lachmann, Mira Choi, Fabian Halleck, Katja Kotsch

J Clin Invest. 2021 Jul 15;131(14):e150175. doi: 10.1172/JCI150175

Immunogenicity of COVID-19 Tozinameran Vaccination in Patients on Chronic Dialysis. Eva Schrezenmeier, Leon Bergfeld, David Hillus, Joerg-Detlef Lippert, Ulrike Weber, Pinkus Tober-Lau, Irmgard Landgraf, Tatjana Schwarz, Kai Kappert, Ana-Luisa Stefanski, Arne Sattler, Katja Kotsch, Thomas Dörner, Leif Erik Sander, Klemens Budde, Fabian Halleck, Florian Kurth, Victor Max Corman, Mira Choi. Front. Immunol. 2021 Jun 30;12:690698. doi: 10.3389/fimmu.2021.690698

Perioperative Perfusion of Allografts with Anti-Human T-lymphocyte Globulin Does Not Improve Outcome Post Liver Transplantation - A Randomized Placebo-Controlled Trial. Ritschl PV, Günther J, Hofhansel L, Ernst S, Ebner S, Sattler A, Weiß S, Weissenbacher A, Oberhuber R, Cardini B, Öllinger R, Biebl M, Denecke C, Margreiter C, Resch T, Schneeberger S, Maglione M, Kotsch K, Pratschke J. J Clin Med. 2021 Jun25;10(13):2816. doi: 10.3390/jcm10132816

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients. Hector Rincon-Arecalo, Mira Choi, Ana-Luisa Stefanski, Fabian Halleck, Ulrike Weber, Franziska Szelinski, Bernd Jahrsdörfer, Hubert Schrezenmeier, Carolin Ludwig, Arne Sattler, Katja Kotsch, Alexander Potekhin, Yidan Chen, Gerd R Burmester, Kai-Uwe Eckardt, Gabriela Maria Guerra, Pawel Durek, Frederik Heinrich, Marta Ferreira-Gomes, Andreas Radbruch, Klemens Budde, Andreia C Lino, Mir-Farzin Mashregi, Eva Schrezenmeier, Thomas Dörner. Sci Immunol. 2021 Jun 15;6(60):eabj1031. doi: 10.1126/sciimmunol.abj1031

Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells. Anna Pascual-Reguant, Ralf Köhler, Ronja Mothes, Sandy Bauherr, Daniela C Hernández, Ralf Uecker, Karolin Holzwarth, Katja Kotsch, Maximilian Seidl, Lars Philipsen, Werner Müller, Chiara Romagnani, Raluca Niesner, Anja E Hauser. Nat Commun. 2021 Mar 19;12(1):1737. doi: 10.1038/s41467-021-21994-8

2020

SARS-CoV-2 specific T-cell responses and correlations with COVID-19 patient predisposition.

Sattler A, Angermair S, Stockmann H, Heim KM, Khadzhynov D, Treskatsch S, Halleck F, Kreis ME, Kotsch KJ Clin Invest. 2020 Aug 24:140965. doi: 10.1172/JCI140965.

Mucosal associated invariant T cells are differentially impaired in tolerant and immunosuppressed liver transplant recipientsSattler A, Thiel LG, Ruhm AH, Bergmann Y, Dornieden T, Choi M, Halleck F, Friedersdorff F, Eurich D, Kotsch KAm J Transplant. 2020 Jun 8

 

Novel methods for in vitro modeling of pancreatic cancer reveal important aspects for successful primary cell culture. Ehlen L, Arndt J, Treue D, Bischoff P, Loch FN, Hahn EM, Kotsch K, Klauschen F, Beyer K, Margonis GA, Kreis ME, Kamphues C. BMC Cancer. 2020 May 13;20(1):417

 

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via TracheostomyRitschl PV, Hofhansel L, Flörchinger B, Oberhuber R, Öllinger R, Pratschke J, Kotsch KJ Vis Exp. 2020 Apr 17;(158).

Perioperative Pleural Drainage in Liver Transplantation: A Retrospective Analysis from a High-Volume Liver Transplant Center. Wiering L, Sponholz F, Brandl A, Dziodzio T, Jara M, Dargie R, Eurich D, Schmelzle M, Sauer IM, Aigner F, Kotsch K, Pratschke J, Öllinger R, Ritschl PV.

Annals Transplant. 2020 Jan 17;25:e918456.

2019

The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells. Sattler A, Thiel LG, Ruhm AH, Souidi N, Seifert M, Herberth G, Kotsch K. J Immunol. 2019 Oct 18. pii: ji1900465

  

Natural Killer Cells Promote Kidney Graft Rejection Independently of Cyclosporine A Therapy.  Ashraf MI, Sarwar A, Kühl AA, Hunger E, Sattler A, Aigner F, Regele H, Sauter M, Klingel K, Schneeberger S, Resch T, Kotsch KFront Immunol. 2019 Sep 24;10:2279.

  

ITS finally here! The first International Transplant Science meeting jointly organized by AST, ESOT, and TTS. Chong AS, Rothstein DM, Issa F, Kotsch K, Leuvenink H, Tullius SG.

Transplantation. 2019 Oct;103(10):1975-1976.

  

Interactions of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer. Beyer K, Baukloh AK, Stoyanova A, Kamphues C, Sattler A, Kotsch K. Cancers (Basel). 2019 Aug 13;11(8).

2018

Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period-a Prospective, Randomized Placebo-Controlled Trial. Ritschl PV, Günther J, Hofhansel L, Kühl AA, Sattler A, Ernst S, Friedersdorff F, Ebner S, Weiss S, Bösmüller C, Weissenbacher A, Oberhuber R, Cardini B, Öllinger R, Schneeberger S, Biebl M, Denecke C, Margreiter C, Resch T, Aigner F, Maglione M, Pratschke J, Kotsch K. Front Immunol. 2018 Aug 24;9:1911

2017

Deletion of the Activating NK Cell Receptor NKG2D Accelerates Rejection of Cardiac Allografts. Fabritius C, Ritschl PV, Resch T, Roth M, Ebner S, Günther J, Mellitzer V, Nguyen AV, Pratschke J, Sauter M, Klingel K and Kotsch KAm J Transplant. Accepted manuscript online: 14 AUG 2017 04:50AM EST | DOI: 10.1111/ajt.14467

 

Disturbances in iron homeostasis result in accelerated rejection after experimental heart transplantation. Resch T, Ashraf MI, Ritschl PV, Ebner S, Fabritius C, Brunner A, Schäfer G, Regele H, Günther J, Weiss G, Kotsch KJ Heart Lung Transplant. 2017 Mar 7. pii: S1053-2498(17)31681-9.

 

Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome. Günther J, Resch T, Hackl H, Sattler A, Ebner S, Ritschl PV, Biebl M, Öllinger R, Schneeberger S, Brandacher G, Schwelberger H, Zelger B, Stauch D, Pascher A, Pratschke J, Kotsch K. Kidney Int. 2017 Feb 20. pii: S0085-2538(17)30002-9

2016

Donor brain death leads to differential immune activation in solid organs but does not accelerate ischaemia-reperfusion injury. Ritschl PV, Ashraf MI, Oberhuber R, Mellitzer V, Fabritius C, Resch T, Ebner S, Sauter M, Klingel K, Pratschke J, Kotsch KJ Pathol. 2016 May;239(1):84-96.

 

Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation. Ashraf MI, Schwelberger HG, Brendel KA, Feurle J, Andrassy J, Kotsch K, Regele H, Pratschke J, Maier HT, Aigner F. Am J Transplant. 2016 Mar;16(3):808-20.

2015

Treatment with tetrahydrobiopterin overcomes brain death-associated injury in a murine model of pancreas transplantation. Oberhuber R, Ritschl P, Fabritius C, Nguyen AV, Hermann M, Obrist P, Werner ER, Maglione M, Flörchinger B, Ebner S, Resch T, Pratschke J, Kotsch K.

Am J Transplant. 2015 Nov;15(11):2865-76. doi: 10.1111/ajt.13364. Epub 2015 Jun 23.

 

IL-15 dependent induction of IL-18 secretion as a feedback mechanism controlling human MAIT-cell effector functions. Sattler A, Dang-Heine C, Reinke P, Babel N. Eur J Immunol. 2015 Aug;45(8):2286-98

The Role of Natural Killer Cells in Humoral RejectionResch T, Fabritius C, Ebner S, Ritschl P, Kotsch KTransplantation. 2015 Jul;99(7):1335-40. 10.1097 Review

 

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice. Tepeköylü C, Lobenwein D, Blunder S, Kozaryn R, Dietl M, Ritschl P, Pechriggl EJ, Blumer MJ, Bitsche M, Schistek R, Kotsch K, Fritsch H, Grimm M, Holfeld J. Eur J Cardiothorac Surg. 2015 Mar;47(3):e80-90. doi: 10.1093/ejcts/ezu428. Epub 2014 Nov 24.

2014

Report of the joint ESOT and TTS basic science meeting 2013: current concepts and discoveries in translational transplantationEbner S, Fabritius C, Ritschl P, Oberhuber R, Günther J, Kotsch KTranspl Int. 2014 Oct;27(10):987-93. doi: 10.1111/tri.12366. Epub 2014 Jun 30. Review.

 

The activating receptor NKG2D of natural killer cells promotes resistance against enterovirus-mediated inflammatory cardiomyopathy. Klingel K, Fabritius C, Sauter M, Göldner K, Stauch D, Kandolf R, Ettischer N, Gahlen S, Schönberger T, Ebner S, Makrigiannis AP, Bélanger S, Diefenbach A, Polić B, Pratschke J, Kotsch KJ Pathol. 2014 Oct;234(2):164-77. doi: 10.1002/path.4369. Epub 2014 Aug 6.

 

NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class I molecules. Sleiman M, Brons NH, Kaoma T, Dogu F, Villa-Forte A, Lenoble P, Hentges F, Kotsch K, Gadola SD, Vilches C, Zimmer J. J Immunol. 2014 Mar 15;192(6):2602-10. doi: 10.4049/jimmunol.1302843. Epub 2014 Feb 19.

 

Differential influenza H1N1-specific humoral and cellular response kinetics in kidney transplant patients. Rambal V, Müller K, Dang-Heine C, Sattler A, Dziubianau M, Weist B, Luu SH, Stoyanova A, Nickel P, Thiel A, Neumann A, Schweiger B, Reinke P, Babel N.

Med Microbiol Immunol. 2014 Feb;203(1):35-45

Bilirubin rinse of the graft ameliorates ischemia reperfusion injury in heart transplantation. 

Bösch F, Thomas M, Kogler P, Oberhuber R, Sucher R, Aigner F, Semsroth S, Wiedemann D, Yamashita K, Troppmair J, Kotsch K, Pratschke J, Öllinger R. Transpl Int. 2014 May;27(5):504-13. doi: 10.1111/tri.12278. Epub 2014 Mar 5.

2013

Isolation of a novel thioflavin S-derived compound that inhibits BAG-1-mediated protein interactions and targets BRAF inhibitor-resistant cell linesEnthammer M, Papadakis ES, Salomé Gachet M, Deutsch M, Schwaiger S, Koziel K, Ashraf MI, Khalid S, Wolber G, Packham G, Cutress RI, Stuppner H, Troppmair J. Mol Cancer Ther. 2013 Nov;12(11):2400-14. doi: 10.1158/1535-7163.MCT-13-0142.

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus. Alexander T, Sattler A, Templin L, Kohler S, Groß C, Meisel A, Sawitzki B, Burmester GR, Arnold R, Radbruch A, Thiel A, Hiepe F. Ann Rheum Dis. 2013 Sep 1;72(9):1549-58

Targeting the Kv1.3 potassium channel for immunosuppression in vascularized composite allotransplantation - a pilot study. Hautz T, Krapf C, Grahammer J, Zelger B, Hickethier T, Seger C, Eberhart N, Wallner C, Messner F, Kotsch K, Griesmacher A, Brandacher G, Lee WP, Margreiter R, Pratschke J, Glossmann H, Schneeberger S. Transpl Int. 2013 May;26(5):552-61. doi: 10.1111/tri.12080. 

 

The genetic predisposition of natural killer cell to BK virus-associated nephropathy in renal transplant patientsTrydzenskaya H, Juerchott K, Lachmann N, Kotsch K, Kunert K, Weist B, Schönemann C, Schindler R, Nickel P, Melzig MF, Hugo C, Thomusch O, Neumann AU, Reinke P, Babel N. Kidney Int. 2013 Aug;84(2):359-65. doi: 10.1038/ki.2013.59. Epub 2013 Mar 13.

 

Adiponectin modulates NK-cell function. Wilk S, Jenke A, Stehr J, Yang CA, Bauer S, Göldner K, Kotsch K, Volk HD, Poller W, Schultheiss HP, Skurk C, Scheibenbogen C. Eur J Immunol. 2013 Apr;43(4):1024-33. doi: 10.1002/eji.201242382. Epub 2013 Mar 1.

 

Synergistic effects of prolonged warm ischemia and donor age on the immune response following donation after cardiac death kidney transplantation. Denecke C, Yuan X, Ge X, Kim IK, Bedi D, Boenisch O, Weiland A, Jurisch A, Kotsch K, Pratschke J, Reutzel-Selke A, Tullius SG. Surgery. 2013 Feb;153(2):249-61. doi: 10.1016/j.surg.2012.07.035. Epub 2012 Oct 9.

2012

Decreased levels of serum complement C3 and natural killer cells add to the predictive value of total immunoglobulin G for severe infection in heart transplant recipients. Sarmiento E, del Pozo N, Gallego A, Fernández-Yañez J, Palomo J, Villa A, Ruiz M, Muñoz P, Rodríguez C, Rodríguez-Molina J, Navarro J, Kotsch K, Fernandez-Cruz E, Carbone J. Transpl Infect Dis. 2012 Oct;14(5):526-39. doi: 10.1111/j.1399-3062.2012.00757.x.

 

Induction of bona fide regulatory T cells after liver transplantation - the potential influence of polyclonal antithymocyte globulin. Stauch D, Yahyazadeh A, Bova R, Melloh GC, Füldner A, Baron U, Olek S, Göldner K, Weiss S, Pratschke J, Kotsch KTranspl Int. 2012 Mar;25(3):302-13. doi: 10.1111/j.1432-2277.2011.01405.x. 

2011

Novel approach for improved assessment of phenotypic and functional characteristics of BKV-specific T-cell immunity. Trydzenskaya H, Sattler A, Müller K, Schachtner T, Dang-Heine C, Friedrich P, Nickel P, Hoerstrup J, Schindler R, Thiel A, Melzig MF, Reinke P, Babel N.

Transplantation. 2011 Dec 15;92(11):1269-77

 

In vivo effect of bone marrow-derived mesenchymal stem cells in a rat kidney transplantation model with prolonged cold ischemia. Hara Y, Stolk M, Ringe J, Dehne T, Ladhoff J, Kotsch K, Reutzel-Selke A, Reinke P, Volk HD, Seifert M. Transpl Int. 2011 Nov;24(11):1112-23. doi: 10.1111/j.1432-2277.2011.01328.x. Epub 2011 Aug 31.

 

Expression of functional T-cell markers and T-cell receptor Vbeta repertoire in endomyocardial biopsies from patients presenting with acute myocarditis and dilated cardiomyopathy. Noutsias M, Rohde M, Göldner K, Block A, Blunert K, Hemaidan L, Hummel M, Blohm JH, Lassner D, Kühl U, Schultheiss HP, Volk HD, Kotsch KEur J Heart Fail. 2011 Jun;13(6):611-8. doi: 10.1093/eurjhf/hfr014. Epub 2011 Mar 19.

 

BK-VP3 as a new target of cellular immunity in BK virus infection. Mueller K, Schachtner T, Sattler A, Meier S, Friedrich P, Trydzenskaya H, Hinrichs C, Trappe R, Thiel A, Reinke P, Babel N. Transplantation. 2011 Jan 15;91(1):100-7

2010

Novel markers in zero-hour kidney biopsies indicate graft quality and clinical outcome. Kotsch K, Kunert K, Merk V, Reutzel-Selke A, Pascher A, Fritzsche F, Tullius SG, Pratschke J. Transplantation. 2010 Nov 15;90(9):958-65.

 

Perioperative gene expression analysis for prediction of postoperative sepsis. Hinrichs C, Kotsch K, Buchwald S, Habicher M, Saak N, Gerlach H, Volk HD, Keh D. Clin Chem. 2010 Apr;56(4):613-22. doi: 10.1373/clinchem.2009.133876. 

2009

Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptorPinkert S, Westermann D, Wang X, Klingel K, Dörner A, Savvatis K, Grössl T, Krohn S, Tschöpe C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H. Circulation. 2009 Dec 8;120(23):2358-66

 

Intracellular signaling pathways control mitochondrial events associated with the development of ischemia/ reperfusion-associated damageSucher R, Gehwolf P, Kaier T, Hermann M, Maglione M, Oberhuber R, Ratschiller T, Kuznetsov AV, Bösch F, Kozlov AV, Ashraf MI, Schneeberger S, Brandacher G, Ollinger R, Margreiter R, Troppmair J. Transpl Int. 2009 Sep;22(9):922-30. doi: 10.1111/j.1432-2277.2009.00883.x

 

Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditisJäkel S, Kuckelkorn U, Szalay G, Plötz M, Textoris-Taube K, Opitz E, Klingel K, Stevanovic S, Kandolf R, Kotsch K, Stangl K, Kloetzel PM, Voigt A. Am J Pathol. 2009 Aug;175(2):510-8. doi: 10.2353/ajpath.2009.090033. Epub 2009 Jul 9.

 

Role of NK and NKT cells in solid organ transplantationPratschke J, Stauch D, Kotsch KTranspl Int. 2009 Sep;22(9):859-68. doi: 10.1111/j.1432-2277.2009.00884.x. Epub 2009 Apr 21. Review.

 

Cold ischemia does not interfere with tolerance inductionReutzel-Selke A, Hartmann J, Brandenburg P, Jurisch A, Francuski M, Ulrich F, Kotsch K, Pascher A, Neuhaus P, Tullius SG, Pratschke J. Transplantation. 2009 Apr 27;87(8):1116-24. doi: 10.1097/TP.0b013e31819dfb29

 

Targeting of natural killer cells by rabbit antithymocyte globulin and campath-1H: similar effects independent of specificityStauch D, Dernier A, Sarmiento Marchese E, Kunert K, Volk HD, Pratschke J, Kotsch KPLoS One. 2009;4(3):e4709. doi: 10.1371/journal.pone.0004709. Epub 2009 Mar 5.

 

Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissueWieczorek G, Asemissen A, Model F, Turbachova I, Floess S, Liebenberg V, Baron U, Stauch D, Kotsch K, Pratschke J, Hamann A, Loddenkemper C, Stein H, Volk HD, Hoffmüller U, Grützkau A, Mustea A, Huehn J, Scheibenbogen C, Olek S. Cancer Res. 2009 Jan 15;69(2):599-608. doi: 10.1158/0008-5472.CAN-08-2361.

 

Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammationSattler A, Wagner U, Rossol M, Sieper J, Wu P, Krause A, Schmidt WA, Radmer S, Kohler S, Romagnani C, Thiel A. Blood. 2009 Feb 26;113(9):1948-56

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune systemAlexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F. Blood. 2009 Jan 1;113(1):214-23 

SHIP limits immunoregulatory capacity in the T-cell compartmentCollazo MM, Wood D, Paraiso KH, Lund E, Engelman RW, Le CT, Stauch D, Kotsch K, Kerr WG. Blood. 2009 Mar 26;113(13):2934-44. doi: 10.1182/blood-2008-09-181164.

Amplifying the fluorescence of bilirubin enables the real-time detection of heme oxygenase activityKlemz R, Mashreghi MF, Spies C, Volk HD, Kotsch KFree Radic Biol Med. 2009 Jan 15;46(2):305-11.

2008

Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trialKotsch K, Ulrich F, Reutzel-Selke A, Pascher A, Faber W, Warnick P, Hoffman S, Francuski M, Kunert C, Kuecuek O, Schumacher G, Wesslau C, Lun A, Kohler S, Weiss S, Tullius SG, Neuhaus P, Pratschke J. Ann Surg. 2008 Dec;248(6):1042-50.

NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy. Streitz M, Noutsias M, Volkmer R, Rohde M, Brestrich G, Block A, Klippert K, Kotsch K, Ay B, Hummel M, Kühl U, Lassner D, Schultheiss HP, Volk HD, Kern F. PLoS One. 2008 Jun 4;3(6):e2361. doi: 10.1371/journal.pone.0002361.

 

Inhibition of dendritic cell maturation and function is independent of heme oxygenase 1 but requires the activation of STAT3. Mashreghi MF, Klemz R, Knosalla IS, Gerstmayer B, Janssen U, Buelow R, Jozkowicz A, Dulak J, Volk HD, Kotsch K.

 

Ischemic preconditioning produces systemic protective and adoptively transferable effects. 

Reutzel-Selke A, Pratschke J, Martins PN, Denecke C, Jurisch A, Kotsch K, Pascher A, Neuhaus P, Tullius SG. Kidney Int. 2008 Sep;74(5):622-30. doi: 10.1038/ki.2008.208. Epub 2008 May 28.

 

Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies.  Noutsias M, Rohde M, Block A, Klippert K, Lettau O, Blunert K, Hummel M, Kühl U, Lehmkuhl H, Hetzer R, Rauch U, Poller W, Pauschinger M, Schultheiss HP, Volk HD, Kotsch K.

BMC Mol Biol. 2008 Jan 14;9:3. doi: 10.1186/1471-2199-9-3.

2007

KIR/HLA ligand incompatibility in kidney transplantation. Kunert K, Seiler M, Mashreghi MF, Klippert K, Schönemann C, Neumann K, Pratschke J, Reinke P, Volk HD, Kotsch KTransplantation. 2007 Dec 15;84(11):1527-33.

 

Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration. Kotsch K, Martins PN, Klemz R, Janssen U, Gerstmayer B, Dernier A, Reutzel-Selke A, Kuckelkorn U, Tullius SG, Volk HD. Antioxid Redox Signal. 2007 Dec;9(12):2049-63.

Skin disease is prevented but nephritis is accelerated by multiple pregnancies in autoimmune MRL/LPR mice. Kökény G, Godó M, Nagy E, Kardos M, Kotsch K, Casalis P, Bodor C, Rosivall L, Volk HD, Zenclussen AC, Hamar P. Lupus. 2007;16(7):465-77.

 

Intrarenal cytokine and chemokine gene expression and kidney graft outcome. Hribova P, Lacha J, Kotsch K, Volk HD, Brabcova I, Skibova J, Vitko S, Viklicky O. Kidney Blood Press Res. 2007;30(5):273-82. Epub 2007 Jul 4.

Brain death activates donor organs and is associated with a worse I/R injury after liver transplantation. Weiss S, Kotsch K, Francuski M, Reutzel-Selke A, Mantouvalou L, Klemz R, Kuecuek O, Jonas S, Wesslau C, Ulrich F, Pascher A, Volk HD, Tullius SG, Neuhaus P, Pratschke J. Am J Transplant. 2007 Jun;7(6):1584-93. Epub 2007 Apr 8.

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